Dr. Oh-Lee received a B.A. degree from Colorado College and his Master’s & Ph.D. degree from the University of California, Los Angeles (UCLA) where he worked on the nerve growth factor receptor, p75, in Alzheimer’s disease pathogenesis. For postdoctoral training, he received an Intramural Research Training Award (IRTA) fellowship (1995-1999) and worked as a research fellow (1999-2001) at the Clinical Pharmacology Section, Experimental Therapeutics Branch, NINDS, National Institutes of Health, Bethesda, Maryland, studying neurobiological and neuropharmacological basis of motor and response complications in Parkinson’s disease. He joined the Department of Psychology at Central Michigan University (CMU) as an assistant professor in 2001 where he now serves as a Co-director of the BRAIN Center at CMU. His current research interests include studies in neuronal plasticity and neuronal degenerative processes, particularly those that are associated with neurodegenerative disorders such as Parkinson’s disease, Alzheimer’s disease, and other related neurological diseases.
Ryan Wessell (Ph.D. Student)
Jennifer Basse (Master's Student)
Syed M. Ahmed (Research Assistant)
Bibbiani,
F and Oh, J.D., Petzer, J.P., Castagnoli, N., Chen, J.-F., Schwarzchild, M.A.,
and Chase, T.N. (2003). (in press) A2A antagonist prevents dopamine
agonist-induced motor complications in animal models of PD. Experimental
Neurology.
Chase,
T.N., Bibbiani, F., and Oh, J.D.
(2003) Striatal Glutamatergic Mechanisms and Extrapyramidal Movement Disorders. Neurotoxicity
Research.
Oh,
J.D., Chartisathian, K, Ahmed, S.M., and Chase, T.N. (2003) Cyclic AMP
responsive element binding protein (CREB) Phosphorylation and Persistent
Expression of Levodopa-induced Response Alterations in Parkinsonian Rats. Journal
of Neuroscience Research.
Oh,
J.D., Geller, A.I., Zhang, G.R., Chase, T.N. (2003) Gene transfer of
constitutively active protein kinase C into striatal neurons accelerates onset
of levodopa-induced motor response alterations in parkinsonian rats. Brain
Research.
Oh,
J.D., Bibbiani, F., Chase, T.N. (2002) Quetiapine Attenuates Levodopa-induced
Motor Complications in Rodent and Primate Parkinsonian Models. Experimental
Neurology.
Metman,
L.V. and Oh, J.D. (2002) Dyskinesias in
Parkinson’s Disease; Ionotrophic Glutamate Receptors as Therapeutic
Targets (Ed: Lodge D.; Danysz W.; Parsons CG), pp. 205-225, F.P. Graham
Publishing Co., Johnson City, Tennessee.
Oh,
J.D. and Chase, T.N. (2002) Glutamate-mediated striatal dysregulation and
pathogenesis of Parkinsonian motor response complications, Amino Acids.
Bibbiani,
F., Oh, J.D., Chase, T.N. (2002) Serotonin 5-HT1A agonist improves motor
complications in rodent and primate parkinsonian models. Neurology.
Chase,
T.N., Konitsiotis, S., Oh, J.D. (2001) Striatal molecular mechanisms and motor
dysfunction in Parkinson's disease. Advances In Neurology: PARKINSON'S DISEASE,
86, 355-360.
Bibbiani,
F., Oh, J.D., Chase, T.N. (2001) Serotonin
5-HT1A agonist, sarizotan, attenuates levodopa-induced motor complications in
rodent and primate parkinsonian models. Neurology.
Zhong
L.T., Manzi, A., Skowronski, E., Notterpek, L., Fluharty, A.L., Faull, K.F.,
Masada, I., Rabizadeh, S., Varsanyi-Nagy, M., Ruan, Y.L., Oh, J.D., Butcher, L.L.,
Bredesen, D.E. (2001) A monoclonal antibody that induces neuronal apoptosis
binds a metastasis marker. Cancer Research.
Chase,
T.N., Konitsiotis, S. and Oh, J.D., (2000), Striatal Molecular Mechanisms and
Motor Dysfunction in Parkinson’s Disease, In
Parkinson’s disease: Advances in
Neurology, Vol. 86, (Ed. Calne D and Calne S), Lippincott Williams &
Wilkins.
Chase, T.N. and Oh, J.D. (2000), Striatal dopamine- and glutamate-mediated dysregulation in experimental parkinsonism. Trends in Neuroscience.
Oh, J.D., Chartisathian, K., Chase, T.N. and Butcher, L.L. (2000), Overexpression of neurotrophin receptor p75 contributes to the excitotoxin-induced cholinergic cell death in the rat basal forebrain. Brain Research.
Chase, T.N., Oh, J.D. and Konitsiotis, S. (2000) Antiparkinsonian and antidyskinetic activity of drugs targeting central glutamatergic mechanisms, Journal of Neurology.
Chase, T.N. and Oh, .JD. (2000) Striatal mechanisms and pathogenesis of Parkinsonian signs motor complications. Ann. Neurology.